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The invention of the induced pluripotent stem cell (iPSC) technology allows patient-specific, mature somatic cells to be converted into an unlimited supply of pluripotent stem cells (PSCs) ...
Myocardial infarction (MI) is associated with damage to the myocardium which results in a great loss of functional cardiomyocytes. As one of the most terminally differentiated organs, the endogenous regenerative potentials of adult hearts are extremely limited and insufficient to compensate for the myocardial loss occurring after MI ...
Article Lu Cai and Bradley B Keller "Cardiac regeneration and diabetes"
The prevalence of diabetes continues to increase world-wide and is a leading cause of morbidity, mortality, and rapidly rising health care costs. Although strict glucose control combined with good pharmacological and non-pharmacologic interventions can increase diabetic patient life span, the frequency and mortality of myocardial ischemia and infarction remain drastically increased in diabetic patients ...
Article Y James Kang and Lily Zheng "Rejuvenation: an integrated approach to regenerative medicine"
Regenerative medicine is an integrated process to recover the organ function lost due to age, disease, damage, or congenital defects. The existing approaches for this process include transplantation, tissue engineering, cell therapy, and gene therapy ...
Article Jibing Yang and Zhenquan Jia "Cell-based therapy in lung regenerative medicine"
The lung disease has become one of the major public health issues across the world with the increased human activities, environmental changes, air pollution, smoking, and various pathogens like influenza ...
Article Na Li, Chuan Wang, LiXin Jia, Jie Du "Heart regeneration, stem cells, and cytokines"
The human heart has limited regenerative capacity, which makes the reparative response after the cardiac infarction quite challenging ...
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